I am going to approach this article from from the viewpoint of your well-being and mental state, as opposed to some of the more practical issues you are likely to encounter.
Let's assume the Thai girl of your dreams just happens to have originated in a small village of about 150 people, right up in the north east part of Issan, some 130km from Udon Thani, and still many kiliometers from the next largest city of Sakon Nakhon. What you likely to face is a village with no other foreigners, and no locals that can speak your language, a handful of shops selling the same day to day goods, and precious little else. Internet connections, way out in the sticks, cannot be classed as reliable, or even good (sometimes non-existent), so to rely on communication with the outside world by that method, could be a non-starter too. How do you think you would cope with being cut off from the outside world, to an extent you have not previously encountered? My guess is that you would probably either go mad within a few years, or begin the slippery slope in to a form of depression, as the isolation may become too much over time.
While you can drive a car or moped to a more local town, or even to Udon Thani, to try and establish some kind of social life beyond your new, immediate family, this is not a straight forward solution, and is actually quite unpractical to an extent. If you are planning on having a few alcoholic drinks, how will you get back home? or is there a hotel or guesthouse you can stay for the night? How often do you think you can do this for?
If possible, from your point of view and well-being, I would suggest you try to live not much more than perhaps 10km from a city of large town. At least you will probably have some public transport available, and even tuk tuk's, which are scarce in the small villages beyond.
If you can afford to buy land or a house in Udon Thani, so much the better but prices are climbing quite sharply now. There is normally a range or reasonably or well priced pieces of land available in the surrounding villages, up to about 4 or 5km from the Udon Thani ring road, which are well worth contemplating.
Having lived here for just under 4 years now, and 2 of those in a small village a few kilometers from Udon Thani, I would not want to be much further away from the city. The main reason for that is the social element. My wife speaks English well enough to talk day to day, but the conversation is often quite limited and I need more than talking about food, prices, and what here brothers are doing etc.
I try to get to Udon Thani city at least once a week, even if it is just for a few hours in the afternoon, to get out of the house, meet new people and friends, or perhaps treat myself to a massage (which is also not available in the village), and indulge a little in a western cooked meal. It took me three years of staying at home with the family to get to the point where I realised I just had to get out and do my own thing, with like minded ex-pats. It has given me a new lease of life, and it was not until I began to do this, that I realised just how isolated I previously was. For those few years, I told myself I was content staying at home most of the time but in reality I that just was not 100% true. Something had to change, and just by spending a few hours in the Udon Thani 'Ferangland' has made the world of difference to my personal well-being.